Architecture of β-barrel membrane proteins: Analysis of trimeric porins
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چکیده
منابع مشابه
A 3-Dimensional Trimeric β-Barrel Model for Chlamydia MOMP Contains Conserved and Novel Elements of Gram-Negative Bacterial Porins
Chlamydia trachomatis is the most prevalent cause of bacterial sexually transmitted diseases and the leading cause of preventable blindness worldwide. Global control of Chlamydia will best be achieved with a vaccine, a primary target for which is the major outer membrane protein, MOMP, which comprises ~60% of the outer membrane protein mass of this bacterium. In the absence of experimental stru...
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Integral membrane proteins fall into two major structural classes; they consist of individual or bundled TM -helices, or they form monomeric, dimeric, or trimeric TM -barrels. These folds are dictated by the necessity to form oriented hydrogenbonded secondary structures in the highly ordered apolar environment of the lipid bilayer. No other structural motif has yet been confirmed for membrane p...
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ژورنال
عنوان ژورنال: Protein Science
سال: 1998
ISSN: 0961-8368,1469-896X
DOI: 10.1002/pro.5560070919